WebJun 10, 2024 · Trabectedin is the name of a chemotherapy drug. It is also known as Yondelis. It is a treatment for: soft tissue sarcoma that has spread to other parts of the … WebMay 3, 2024 · Beginning 2 weeks after the first dose of Trabectedin, all patients will be treated with Ipilimumab at 1 mg/kg every 12 weeks up to 5 doses, and Nivolumab at 3 mg/kg every 2 weeks up to 26 doses. Phase 2: All patients will be treated with the maximum tolerated dose of Trabectedin every 3 weeks. Beginning 2 weeks after the first dose of ...
Uterine Sarcoma Treatment Regimens - Cancer Therapy Advisor
WebTrabectedin injection is used to treat liposarcoma (a cancer that begins in fat cells) or leiomyosarcoma (a cancer that begins in smooth muscle tissue) that has spread to other parts of the body and cannot be treated with surgery in people who have already been treated with certain chemotherapy medications. WebMar 12, 2015 · Trabectedin is a tetrahydroisoquinoline molecule that binds to the N2 of guanine in the minor groove, causing DNA damage and affecting transcription regulation in a promoter- and gene-specific manner. tamarin spice liver cleanse
Trabectedin, a drug acting on both cancer cells and the tumour
WebTrabectedin is approved to treat: Liposarcoma and leiomyosarcoma (types of soft tissue sarcoma) that cannot be removed by surgery or have metastasized (spread to other parts of the body). It is used in patients who have already been … WebAug 8, 2014 · In this mini-review, we will outline the current state of knowledge regarding the mode of action of trabectedin, which appears to represent a new class of anti-neoplastic … WebYONDELIS (trabectedin) for injection, for intravenous use Initial U.S. Approval: 2015 -----INDICATIONS AND USAGE----- YONDELIS is an alkylating drug indicated for the treatment of patients with unresectable or metastatic liposarcoma or leiomyosarcoma who received a tamarins service 974