Tagln smooth muscle

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August undefined, 2024

WebApr 6, 2024 · This gene encodes the actin-binding protein transgelin, which is abundant in vascular and visceral smooth muscle, and it is an early marker of smooth muscle differentiation. The authors of [ 46 ] found that by inducing filamentous actin bundling, TAGLN facilitated the reorganization of the cytoskeleton and maintained the contractile … WebApr 6, 2024 · Smooth muscle cell (SMC) is a key component in neointimal hyperplasia in venous stenosis [6, 7]. ... SMCs were defined by Acta2 and Tagln (encoding SM22), while clusters 3 and 11 were defined as SPCs as they exclusively expressed Ly6a and Cd34 (Fig. S1C). Notably, compared to healthy vessels, Malat1 was downregulated in both AS groups …

Vascular Smooth Muscle Progenitor Cells Circulation Research

WebNine genes were defined as hub genes: transgelin (TAGLN), alpha-smooth muscle actin (ACTA2), myosin heavy chain 11 (MYH11), caldesmon 1 (CALD1), myosin light chain kinase (MYLK), GTP-binding protein overexpressed in skeletal muscle (GEM), proline and arginine rich end leucine-rich repeat protein (PRELP), tropomyosin 2 (TPM2), and osteoglycin (OGN). WebMar 21, 2024 · TAGLN (Transgelin) is a Protein Coding gene. Diseases associated with TAGLN include Peyronie Disease and Aortic Dissection. Among its related pathways are … golf club fitting san antonio texas

Smooth Muscle Cells Markers - CUSABIO

WebSep 19, 2024 · The effect of TAGLN was evaluated both in vitro and in vivo using transwell assay, immunofluorescence, western blot analysis and immunohistochemistry. Results: … WebJul 25, 2024 · The vascular smooth muscle cell (SMC) is a differentiated cell type located within the medial layer of arteries and veins and expressing a unique repertoire of proteins (eg, MYH11 [smooth muscle myosin heavy chain], ACTA2 [smooth muscle alpha-actin], TAGLN [sm22 alpha], and MYOCD [myocardin]) required for their contractile function. 1 … WebOffriamo un ampio portafoglio di anticorpi policlonali di alta qualità da utilizzare in molteplici applicazioni di ricerca. ️ Prodotti di alta qualità ️ Prezzi bassi ️ Garanzia al 100% healey lincoln - goshen

Transgelin/TAGLN/SM22 alpha Antibody (NB600-507): Novus …

Web004746 STOCK Tg(Tagln-cre)1Her/J A C57BL/6 congenic version of this strain is available as Stock No. 017491 . These transgenic mice express Cre recombinase under the control of the mouse transgelin (smooth muscle protein 22-alpha) promoter. Cre recombinase activity is observed in vascular smooth muscle cells of hepatic and pulmonary arteries. WebAug 2, 2024 · The actin-crosslinking protein TAGLN (transgelin, also known as SM22 or SM22α) is abundantly expressed in smooth muscle cells … healey lodge nursing homeWebJul 15, 2024 · Depleting alpha-smooth muscle actin (α-SMA)-expressing cells or inhibiting sonic hedgehog (Shh), a ligand that could activate CAFs, induced ... (TAGLN), myosin regulatory light chain 9 (MYL9), and tropomyosin 1 (TPM1). The pathways enriched in myCAFs were identified by gene set enrichment analysis (GSEA), including smooth … healey lincoln ford

"WebJul 7, 2024 · TAGLN is an actin-binding protein family that comprises three isoforms with theorized roles in smooth muscle differentiation, tumour development, lymphocyte activation, and brain chemistry. " - Tagln smooth muscle

Tagln smooth muscle

Anti-TAGLN/Transgelin antibody (ab10135) Abcam

WebTransgelin is one of the earliest markers of differentiated smooth muscle cells and recent evidence suggests that transgelin acts as a tumor suppressor. Canine (100%), Bovine (100%). Backed by our 100% Guarantee. Test in a species/application not listed above to receive a full credit towards a future purchase. Web017491 B6.Cg-Tg(Tagln-cre)1Her/J These Tagln-cre (also called Sm22aCre) transgenic mice express Cre recombinase under the control of the mouse smooth muscle protein 22-alpha …

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Webfan_ovary_cl17_putative_apoptotic_smooth_muscle_cell https: ... rrs1 sbds selenok selenom selenos serpinh1 sfpq slc25a3 slc25a5 slc3a2 sod1 sod3 sqstm1 srrm2 stat3 stip1 stom taf7 tagln tcp1 timp3 tinagl1 tm4sf1 tmem165 tnfrsf12a tnfrsf1a tpm1 tpm2 tsc22d1 tssc4 tuba1b tuba1c tubb4b uba2 ube2d3 ube2s vasn wdr43 xbp1 ybx1 ybx3 zbtb38 zfhx3 ... WebSmooth muscle cells - Muscle contraction (mainly) Tissue cell type classification i Genes can have enriched specificity in different cell types in one or several tissues, or be …

WebWir bieten ein großes Portfolio an hochwertigen polyklonale Antikörper für den Einsatz in zahlreichen Forschungsanwendungen. ️ Produkte mit hoher Qualität ️ Niedrige Preise ️ 100% Garantie WebApr 25, 2024 · However, the role of TEAD1 in the development of vascular smooth muscle cell (VSMC) is unknown. To investigate cell-specific role of Tead1, we generated cardiomyocyte (CMC) and VSMC-specific Tead1 ...

WebMay 30, 2024 · Here, we find that mesoderm-derived pericytes (PCs) and smooth muscle cells (SMCs) originate from a clonal mesenchymal progenitor mesenchymoangioblast (MB). In clonogenic cultures, ... TAGLN, RGS5, PDGFRB, and ANGPT1 SMC and PC genes between mural cell populations generated from H1 hESCs was confirmed using qPCR (Figure S5 C). WebAug 23, 2024 · Airway smooth muscle (ASM) is a dynamic and complex tissue involved in regulation of bronchomotor tone, but the molecular events essential for the maintenance of ASM homeostasis are not well understood. Observational and genome-wide association studies in humans have linked airway function to the nutritional status of vitamin A and its …

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healey lincoln goshen nyWebJul 7, 2024 · An actin cross-linking protein TAGLN (Transgelin, SM22 or SM22alpha) is abundantly expressed in smooth muscle cells (SMCs) and widely used as its canonical … healey listWebWe have generated transgenic mouse lines expressing a tamoxifen-activated Cre recombinase, CreER (T2), under the control of the smooth muscle-specific SM22 promoter. Both a randomly integrated transgene [SM-CreER (T2) (tg)] and a transgene that has been "knocked in" into the endogenous SM22 locus [SM-CreER (T2) (ki)] were expressed in … healey loggingWebAug 26, 2024 · Mechanical Forces and Smooth Muscle Cells. Cardiovascular diseases are one of the leading causes of global death in developing countries [].More than 80% of cardiovascular disease-associated mortality is attributable to atherosclerosis, a chronic inflammatory disease of the vessel wall [].During the development of atherosclerosis and … healey lodgeWebMay 18, 2015 · SMCs are distinguished from other cell types by expression of a unique repertoire of genes including Acta2, Tagln, and Myh11. These genes are coordinately … healey locationsWebTransgelin is a protein that in humans is encoded by the TAGLN gene. The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling … healey lordWebMar 21, 2024 · SM22; SMCC; TAGLN1; WS3-10; SM22-alpha. Summary. This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the … healey lounge chair